Chemistry For Your Life

#048 Rebroadcast

New College-Style Sweatshirt!

And the Ghost Halloween Design is Back!

This week, Melissa and Jam dive into spiciness. What is it? Is it a flavor? Is it a feeling? Is it both? Is it more? Why can some people handle more than others? Does spiciness have any benefits?

References from this episode

1. https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/vanilloids


2. Solomon’s Organic Chemistry 11th edition


3. Analogues of Capsaicin with Agonist Activity as Novel Analgesic agents; Structure-Activity Studies 2. The Amide Bond “B-Reigion” byWalpole et. al


4. Similarities and Differences in the Structure−Activity Relationships of Capsaicin and Resiniferatoxin Analogues by Walpole et. al


5. Detailed Analysis of the Binding Mode of Vanilloids to Transient Receptor Potential Vanilloid Type I (TRPV1) by a Mutational and Computational Study by Ohbuchi et. al


6. The Art and Science of Organic andNatural Products Synthesis - by Nicolau et. al


7. https://www.acs.org/content/acs/en/pressroom/reactions/videos/2015/why-are-hot-peppers-hot-and-how-milk-helps.html
   

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• Lyn Stubblefield


• Jacob Taber


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#196

New College-Style Sweatshirt!

Melissa and Jam delve into the science behind ibuprofen, exploring why it takes around 30 minutes to work. The discussion covers the chemistry of ibuprofen, including the concept of chiral molecules and enantiomers—molecules with mirror-image forms—highlighting how only one form of ibuprofen works effectively. The episode explains why both forms are included in the medication due to production challenges and discusses recent findings about ibuprofen's potential in cancer treatment. Additionally, the show features various fun facts about ibuprofen, aspirin comparisons, environmentally friendly production methods, and more.

00:00 Introduction and Episode Overview

05:07 Chemistry Lesson: Handedness of Molecules

17:52 Ibuprofen's Chiral Nature and Its Effects

19:15 The Racemic Mixture of Ibuprofen

24:06 The Wastefulness of Chemistry

24:29 Challenges of Purifying Enantiomers

25:16 Economic and Environmental Considerations

26:28 Understanding Ibuprofen's Handedness

27:26 The Debate on Enantiomer Separation

34:45 Fun Facts About Ibuprofen

39:55 Green Chemistry and Ibuprofen

45:42 Community and Closing Remarks

References from this episode:

1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276492/


2. https://thispodcastwillkillyou.com/wp-content/uploads/2021/07/TPWKY-Episode-29-Aspirin.pdf


3. https://www.chemistryworld.com/podcasts/ibuprofen/4011375.article


4. https://pubs.acs.org/doi/epdf/10.1021/bi010045s?ref=article_openPDF


5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355401/ 6. Garret & Grisham Biochemistry Textbook

We want to give a special thanks to Bri McAllister for illustrating molecules for some episodes! Please go check out Bri’s art, follow and support her at entr0pic.artstation.com and @McAllisterBri on twitter!

 

Thanks to our monthly supporters

• Scott B


• Jessie Reder


• Ciara Linville


• J0HNTR0Y


• Jeannette Napoleon


• Cullyn R


• Erica Bee


• Elizabeth P


• Sarah Moar


• Rachel Reina


• Letila


• Katrina Barnum-Huckins


• Suzanne Phillips


• Venus Rebholz


• Lyn Stubblefield


• Jacob Taber


• Brian Kimball


• Emerson Woodhall


• Kristina Gotfredsen


• Timothy Parker


• Steven Boyles


• Chris Skupien


• Chelsea B


• Bri McAllister


• Avishai Barnoy


• Hunter Reardon

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Question and Response #60

New College-Style Sweatshirt!

In this episode of 'Ask a Chemist' on the Chemistry for Your Life podcast, hosts Melissa and Jam tackle a diverse range of fun and fascinating chemistry questions. Topics include the differences between oxygen in water and air, the properties of jello, the mystery behind glitter, and the impact of pasteurization on milk safety. The episode also addresses more complex inquiries such as infrared spectroscopy and the oxidative stability of whole grain flour.

00:00 Introduction to Ask a Chemist

02:39 The Pasteurization Question

08:51 What Makes Jello Jello?

10:06 Oxygen in Water vs. Air

12:40 The Mystery of Glitter

15:46 Infrared Spectroscopy and Northern Lights

18:29 Oxidation in Flour

22:17 Collagen and Muscle Building

26:06 Listener Reviews and Closing Remarks

References from this episode:

1. https://www.maastrichtuniversity.nl/l.vanloon

We want to give a special thanks to Bri McAllister for illustrating molecules for some episodes! Please go check out Bri’s art, follow and support her at entr0pic.artstation.com and @McAllisterBri on twitter!

 

Thanks to our monthly supporters

• Autoclave


• Chelsea M


• Dorien V


• Scott B


• Jessie Reder


• Ciara Linville


• J0HNTR0Y


• Jeannette Napoleon


• Cullyn R


• Erica Bee


• Elizabeth P


• Sarah Moar


• Rachel Reina


• Letila


• Katrina Barnum-Huckins


• Suzanne Phillips


• Venus Rebholz


• Lyn Stubblefield


• Jacob Taber


• Brian Kimball


• Emerson Woodhall


• Kristina Gotfredsen


• Timothy Parker


• Steven Boyles


• Chris Skupien


• Chelsea B


• Bri McAllister


• Avishai Barnoy


• Hunter Reardon

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#195

New College-Style Sweatshirt!

In this episode of Chemistry For Your Life, hosts Melissa and Jam delve into the science behind ibuprofen, a common pain reliever. They discuss the role of prostaglandins in inflammation, how ibuprofen inhibits the cox enzyme to reduce pain, and the body's natural immune response. They also share personal anecdotes about meeting listeners, their favorite types of ibuprofen, and explore plans for future episodes about other pain relievers.

00:00 Introduction and Personal Anecdote

01:00 Meet the Hosts

01:11 Exciting Announcements

02:46 Listener Shoutout

05:41 Understanding Pain and Inflammation

06:48 The Role of Prostaglandins

14:38 How Ibuprofen Works

18:15 Personal Experiences with Pain

21:16 Preview of Next Episode

22:10 Understanding Pain and Inflammation

23:07 The Role of Prostaglandins

24:50 Enzymes and Their Functions

27:11 How Ibuprofen Works

35:11 Personal Experiences with Ibuprofen

40:42 Supporting the Show and Final Thoughts

References from this episode:

1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276492/


2. https://thispodcastwillkillyou.com/wp-content/uploads/2021/07/TPWKY-Episode-29-Aspirin.pdf


3. https://www.chemistryworld.com/podcasts/ibuprofen/4011375.article


4. https://pubs.acs.org/doi/epdf/10.1021/bi010045s?ref=article_openPDF


5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355401/ 6. Garret & Grisham Biochemistry Textbook

We want to give a special thanks to Bri McAllister for illustrating molecules for some episodes! Please go check out Bri’s art, follow and support her at entr0pic.artstation.com and @McAllisterBri on twitter!

 

Thanks to our monthly supporters

• Scott B


• Jessie Reder


• Ciara Linville


• J0HNTR0Y


• Jeannette Napoleon


• Cullyn R


• Erica Bee


• Elizabeth P


• Sarah Moar


• Rachel Reina


• Letila


• Katrina Barnum-Huckins


• Suzanne Phillips


• Venus Rebholz


• Lyn Stubblefield


• Jacob Taber


• Brian Kimball


• Emerson Woodhall


• Kristina Gotfredsen


• Timothy Parker


• Steven Boyles


• Chris Skupien


• Chelsea B


• Bri McAllister


• Avishai Barnoy


• Hunter Reardon

★ Support this podcast on Patreon ★
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#060

Chances are you've heard the word "fluoride" said in reference to your teeth. At the dentists office, on your bottle of mouthwash, maybe you've heard it's in tap water? But what is it, what's so special about it, and how does it help our teeth? Does it make them whiter, stronger, or what? Let's find out.

 

References from this episode

1. https://pubs.acs.org/doi/pdf/10.1021/la4008558


2. https://www.mouthhealthy.org/en/fluoride-superhero


3. General Chemistry 2nd edition Flowers, Theopold, Langley, Robinson
   
   

 

Thanks to our monthly supporters

• Autoclave


• Chelsea Morelos


• Dorien Vdb


• Scott Beyer


• Jessie Reder


• Ciara Linville


• J0HNTR0Y


• Jeannette Napoleon


• Cullyn R


• Erica Bee


• Elizabeth P


• Sarah Moar


• Rachel Reina


• Letila


• Katrina Barnum-Huckins


• Suzanne Phillips


• Venus Rebholz


• Lyn Stubblefield


• Jacob Taber


• Brian Kimball


• Emerson Woodhall


• Kristina Gotfredsen


• Timothy Parker


• Steven Boyles


• Chris Skupien


• Chelsea B


• Bri McAllister


• Avishai Barnoy


• Hunter Reardon

★ Support this podcast on Patreon ★
★ Buy Podcast Merch and Apparel ★

Check out our website at chemforyourlife.com

Watch our episodes on YouTube

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